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Ausgewählte Studien in der Übersicht

 

VITAMIN A

Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome.
Lee H1, Ko G1,2.
Sci Rep. 2016 May 16;6:25835. doi: 10.1038/srep25835.

High-level dietary vitamin A enhances T-helper type 2 cytokine production and secretory
immunoglobulin A response to influenza A virus infection in BALB/c mice.
Cui D1, Moldoveanu Z, Stephensen CB.
J Nutr. 2000 May;130(5):1132-9.

 

THIAMIN

Thiamine disulfide as a potent inhibitor of human immunodeficiency virus (type-1) production.
Shoji S1, Furuishi K, Misumi S, Miyazaki T, Kino M, Yamataka K.
Biochem Biophys Res Commun. 1994 Nov 30;205(1):967-75.

 

NIACIN

Niacin analogue, 6-Aminonicotinamide, a novel inhibitor of hepatitis B virus replication and
HBsAg production.
Ren F1, Yang X1, Hu ZW1, Wong VKW2, Xu HY1, Ren JH1, Zhong S1, Jia XJ1, Jiang H1, Hu
JL1, Cai XF1, Zhang WL1, Yao FL1, Yu HB1, Cheng ST1, Zhou HZ1, Huang AL1, Law BYK3, Chen
J4.
EBioMedicine. 2019 Nov;49:232-246. doi: 10.1016/j.ebiom.2019.10.022. Epub 2019 Oct 31.

 

VITAMIN B6

Association of vitamin B6 status with parameters of immune function in early HIV-1 infection.
Baum MK1, Mantero-Atienza E, Shor-Posner G, Fletcher MA, Morgan R, Eisdorfer C, Sauberlich
HE, Cornwell PE, Beach RS.
J Acquir Immune Defic Syndr (1988). 1991;4(11):1122-32.

 

FOLSÄURE

Interactions between serum folate and human papillomavirus with cervical intraepithelial neoplasia risk in a Chinese population-based study.
Yang J1, Yang A2,3, Wang Z1, Wang W1, Wang Z1, Wang Y1, Wang J4, Song J5, Li L6, Lv
W7, Zhao W1, Li D1, Liu H1, Wang C8, Truong A3, Zheng T3, Mason TG2, Ran J2, Hao M1.
Am J Clin Nutr. 2018 Nov 1;108(5):1034-1042. doi: 10.1093/ajcn/nqy160.

 

VITAMIN C

A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice.
Cai Y1, Li YF1, Tang LP1, Tsoi B1, Chen M1, Chen H1, Chen XM1, Tan RR1, Kurihara H1, He RR1.
Biomed Res Int. 2015;2015:675149. doi: 10.1155/2015/675149. Epub 2015 Feb 1.

Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection.
Kim H1,2, Jang M1, Kim Y1, Choi J1, Jeon J1, Kim J3, Hwang YI1, Kang JS1,2, Lee WJ1
J Pharm Pharmacol. 2016 Mar;68(3):406-20. doi: 10.1111/jphp.12529. Epub 2016 Feb 21.

Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection.
Kim Y1, Kim H, Bae S, Choi J, Lim SY, Lee N, Kong JM, Hwang YI, Kang JS, Lee WJ.
Immune Netw. 2013 Apr;13(2):70-4. doi: 10.4110/in.2013.13.2.70. Epub 2013 Apr 30.

 

VITAMIN D

Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren.
Urashima M1, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H.
Am J Clin Nutr. 2010 May;91(5):1255-60. doi: 10.3945/ajcn.2009.29094. Epub 2010 Mar 10.

 

VITAMIN E

Effect of vitamin E and vitamin C combination on experimental influenza virus infection.
Tantcheva LP1, Stoeva ES, Galabov AS, Braykova AA, Savov VM, Mileva MM.
Methods Find Exp Clin Pharmacol. 2003 May;25(4):259-64.

Vitamin E supplementation increases T helper 1 cytokine production in old mice infected with influenza virus.
Han SN1, Wu D, Ha WK, Beharka A, Smith DE, Bender BS, Meydani SN.
Immunology. 2000 Aug;100(4):487-93.

 

ALPHA-LIPONSÄURE

Alpha-lipoic acid is an effective inhibitor of human immuno-deficiency virus (HIV-1) replication.
Baur A1, Harrer T, Peukert M, Jahn G, Kalden JR, Fleckenstein B.

 

PARA-AMINOBENZOESÄURE (PABA)

Action of para-aminobenzoic acid and its combination with acyclovir in herpetic infection.
Akberova SI, Leont'eva NA, Stroeva OG, Galegov GA.
Antibiot Khimioter. 1995 Oct;40(10):25-9.

 

KNOBLAUCH EXTRAKT

Garlic Organosulfur Compounds Reduce Inflammation and Oxidative Stress during Dengue VirusInfection.
Hall A1, Troupin A2, Londono-Renteria B3, Colpitts TM4.
Viruses. 2017 Jun 23;9(7). pii: E159. doi: 10.3390/v9070159.

 

ALOE BLATTSAFT EXTRAKT

Effect of aloin on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza.
Huang CT1, Hung CY2, Hseih YC3, Chang CS4, Velu AB5, He YC4, Huang YL4, Chen TA4, Chen
TC6, Lin CY7, Lin YC8, Shih SR5, Dutta A9.
Author information
Phytomedicine. 2019 Nov;64:152904. doi: 10.1016/j.phymed.2019.152904. Epub 2019 Apr 4.

Ultrasound mediated accelerated Anti-influenza activity of Aloe vera.
Gansukh E1, Gopal J2, Paul D3, Muthu M2, Kim DH1, Oh JW4, Chun S5.
Sci Rep. 2018 Dec 12;8(1):17782. doi: 10.1038/s41598-018-35935-x.

 

APFELPEKTIN

INHIBITION BY CERTAIN POLYSACCHARIDES OF HEMAGGLUTINATION AND OF MULTIPLICATION OF INFLUENZA VIRUS.
Green RH1, Woolley DW.
J Exp Med. 1947 Jun 30;86(1):55-64.

 

BRAUNALGEN EXTRAKT

Antiviral activity of sulfated polysaccharide from the brown algae Laminaria japonica against
avian influenza A (H5N1) virus infection in the cultured cells.
Makarenkova ID, Deriabin PG, L'vov DK, Zviagintseva TN, Besednova NN.
Vopr Virusol. 2010 Jan-Feb;55(1):41-5.

Influenza virus neuraminidase inhibitory activity of phlorotannins from the edible brown alga Ecklonia cava.
Ryu YB1, Jeong HJ, Yoon SY, Park JY, Kim YM, Park SJ, Rho MC, Kim SJ, Lee WS.
J Agric Food Chem. 2011 Jun 22;59(12):6467-73. doi: 10.1021/jf2007248. Epub 2011 May 26.

 

BROKKOLI PFLANZENPULVER

Effect of Broccoli Sprouts and Live Attenuated Influenza Virus on Peripheral Blood Natural Killer Cells: A Randomized, Double-Blind Study.
Müller L1,2, Meyer M3, Bauer RN1,4, Zhou H5, Zhang H5, Jones S1, Robinette C1, Noah
TL1,6, Jaspers I1,6.
PLoS One. 2016 Jan 28;11(1):e0147742. doi: 10.1371/journal.pone.0147742. eCollection 2016.

Effect of broccoli sprouts on nasal response to live attenuated influenza virus in smokers: a randomized, double-blind study.
Noah TL1, Zhang H2, Zhou H2, Glista-Baker E3, Müller L4, Bauer RN5, Meyer M6, Murphy
PC7, Jones S3, Letang B8, Robinette C3, Jaspers I1
PLoS One. 2014 Jun 9;9(6):e98671. doi: 10.1371/journal.pone.0098671. eCollection 2014.

 

GRÜNTEE EXTRAKT

Anti-pandemic influenza A (H1N1) virus potential of catechin and gallic acid.
You HL1, Huang CC2, Chen CJ3, Chang CC4, Liao PL5, Huang ST6.
J Chin Med Assoc. 2018 May;81(5):458-468. doi: 10.1016/j.jcma.2017.11.007. Epub 2017 Dec 26.

Comparison of in vitro antiviral activity of tea polyphenols against influenza A and B viruses and structure-activity relationship analysis.
Yang ZF1, Bai LP2, Huang WB3, Li XZ3, Zhao SS3, Zhong NS4, Jiang ZH5.
Fitoterapia. 2014 Mar;93:47-53. doi: 10.1016/j.fitote.2013.12.011. Epub 2013 Dec 24.

Effects of green tea catechins and theanine on preventing influenza infection among healthcare workers: a randomized controlled trial.
Matsumoto K1, Yamada H, Takuma N, Niino H, Sagesaka YM.
BMC Complement Altern Med. 2011 Feb 21;11:15. doi: 10.1186/1472-6882-11-15.

 

CHLORELLA MIKROALGE

Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial.
Halperin SA1, Smith B, Nolan C, Shay J, Kralovec J.
CMAJ. 2003 Jul 22;169(2):111-7.

 

CURCUMA EXTRAKT

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways.
Dai J1, Gu L2, Su Y2, Wang Q2, Zhao Y2, Chen X2, Deng H2, Li W3, Wang G2, Li K2.
Int Immunopharmacol. 2018 Jan;54:177-187. doi: 10.1016/j.intimp.2017.11.009. Epub 2017 Nov
15.

Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on antiinfluenzavirus infection.
Richart SM1, Li YL2, Mizushina Y3, Chang YY4, Chung TY5, Chen GH5, Tzen JT5, Shia KS6, Hsu
WL7.
J Food Drug Anal. 2018 Jul;26(3):1015-1023. doi: 10.1016/j.jfda.2017.12.006. Epub 2018 Feb 2.

 

LÖWENZAHN WURZELEXTRAKT

Anti-influenza virus effect of aqueous extracts from dandelion.
He W1, Han H, Wang W, Gao B.
Virol J. 2011 Dec 14;8:538. doi: 10.1186/1743-422X-8-538.

 

SALBEI BLATTEXTRAKT

Anti-influenza effect of the major flavonoids from Salvia plebeia R.Br. via inhibition of influenzaH1N1 virus neuraminidase.
Bang S1, Li W2, Ha TKQ3, Lee C1, Oh WK3, Shim SH1.
Nat Prod Res. 2018 May;32(10):1224-1228. doi: 10.1080/14786419.2017.1326042. Epub 2017
May 15.

 

INGWER EXTRAKT

Anti-avian influenza virus H9N2 activity of aqueous extracts of Zingiber officinalis (Ginger) and Allium sativum (Garlic) in chick embryos.
Rasool A1, Khan MU1, Ali MA2, Anjum AA2, Ahmed I1, Aslam A1, Mustafa G1, Masood S3, Ali
MA4, Nawaz M2.
Pak J Pharm Sci. 2017 Jul;30(4):1341-1344.

 

GRANATAPFEL SCHALENEXTRAKT

Anti-Influenza Virus Activity and Phenolic Content of Pomegranate (Punica granatum L.) Peel Extract and Fractions.
Moradi MT1, Karimi A2, Shahrani M2, Hashemi L3, Ghaffari-Goosheh MS2.
Avicenna J Med Biotechnol. 2019 Oct-Dec;11(4):285-291.

Pomegranate (Punica granatum) purified polyphenol extract inhibits influenza virus and has a synergistic effect with oseltamivir.
Haidari M1, Ali M, Ward Casscells S 3rd, Madjid M.
Phytomedicine. 2009 Dec;16(12):1127-36. doi: 10.1016/j.phymed.2009.06.002. Epub 2009 Jul 7.

Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV.
Houston DMJ1,2, Bugert JJ2, Denyer SP1, Heard CM1.
PLoS One. 2017 Jun 30;12(6):e0179291. doi: 10.1371/journal.pone.0179291. eCollection 2017.

 

CITRUS FRUCHTEXTRAKT

Hesperidin attenuates influenza A virus (H1N1) induced lung injury in rats through its antiinflammatory effect.
Ding Z1,2, Sun G1, Zhu Z1.
Antivir Ther. 2018;23(7):611-615. doi: 10.3851/IMP3235. Epub 2018 Apr 6.

Glucosyl hesperidin prevents influenza a virus replication in vitro by inhibition of viral sialidase.
Saha RK1, Takahashi T, Suzuki T.
Biol Pharm Bull. 2009 Jul;32(7):1188-92.

 

SOJA BOHNENEXTRAKT

Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses.
Bedard KM1, Wang ML, Proll SC, Loo YM, Katze MG, Gale M Jr, Iadonato SP.
J Virol. 2012 Jul;86(13):7334-44. doi: 10.1128/JVI.06867-11. Epub 2012 Apr 24.

New functionally-enhanced soy proteins as food ingredients with anti-viral activity.
Turmagambetova AS1, Sokolova NS1, Bogoyavlenskiy AP1, Berezin VE1, Lila MA2, Cheng
DM3, Dushenkov V4.
Virusdisease. 2015 Sep;26(3):123-32. doi: 10.1007/s13337-015-0268-6. Epub 2015 Aug 15.

 

KAROTTEN RÜBENPULVER

Antibacterial, antifungal, and antiviral effects of three essential oil blends.
Brochot A1, Guilbot A1, Haddioui L2, Roques C2,3.
Microbiologyopen. 2017 Aug;6(4). doi: 10.1002/mbo3.459. Epub 2017 Mar 14.

 

LEINSAMEN EXTRAKT

The antiviral action of lignans.
MacRae WD, Hudson JB, Towers GH.
Planta Med. 1989 Dec;55(6):531-5.

 

LYCOPIN (AUS TOMATEN FRUCHTEXTRAKT)

Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide.
Saedisomeolia A1, Wood LG, Garg ML, Gibson PG, Wark PA.
J Nutr Biochem. 2009 Aug;20(8):577-85. doi: 10.1016/j.jnutbio.2008.06.001. Epub 2008 Sep 27.

 

OPC (AUS TRAUBENKERN EXTRAKT)

Inhibition of proanthocyanidin A2 on porcine reproductive and respiratory syndrome virus replication in vitro.
Zhang M1, Wu Q1, Chen Y2, Duan M3, Tian G1, Deng X1, Sun Y2, Zhou T1, Zhang G2, Chen
W3, Chen J1.
PLoS One. 2018 Feb 28;13(2):e0193309. doi: 10.1371/journal.pone.0193309. eCollection 2018.

 

HEIDELBEERE FRUCHTEXTRAKT

Antiviral effects of blueberry proanthocyanidins against Aichi virus.
Joshi SS1, Howell AB2, D'Souza DH3.
Food Microbiol. 2019 Sep;82:202-208. doi: 10.1016/j.fm.2019.02.001. Epub 2019 Feb 6.

 

WALNUSS SCHALENEXTRAKT

The preventive and therapeutic potential of natural polyphenols on influenza.
Bahramsoltani R1, Sodagari HR2, Farzaei MH3,4, Abdolghaffari AH5,6, Gooshe M7, Rezaei
N8,9,10.
Expert Rev Anti Infect Ther. 2016;14(1):57-80. doi: 10.1586/14787210.2016.1120670. Epub 2015
Dec 7.

Anti-human immunodeficiency virus-type 1 activity of constituents from Juglans mandshurica.
Min BS1, Lee HK, Lee SM, Kim YH, Bae KH, Otake T, Nakamura N, Hattori M.
Arch Pharm Res. 2002 Aug;25(4):441-5.

HOLUNDER BEERENEXTRAKT

Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections.
Zakay-Rones Z1, Thom E, Wollan T, Wadstein J.
J Int Med Res. 2004 Mar-Apr;32(2):132-40.

 

CRANBERRY EXTRAKT

The Cranberry Extract Oximacro® Exerts in vitro Virucidal Activity Against Influenza Virus by Interfering With Hemagglutinin.
Luganini A1, Terlizzi ME1, Catucci G2, Gilardi G2, Maffei ME3, Gribaudo G1.
Front Microbiol. 2018 Aug 7;9:1826. doi: 10.3389/fmicb.2018.01826. eCollection 2018.

High molecular weight constituents of cranberry interfere with influenza virus neuraminidase activity in vitro.
Oiknine-Djian E1, Houri-Haddad Y, Weiss EI, Ofek I, Greenbaum E, Hartshorn K, Zakay-Rones Z.
Planta Med. 2012 Jun;78(10):962-7. doi: 10.1055/s-0031-1298579. Epub 2012 May 15.

 

ROSMARINSÄURE (AUS SALBEI BLATTEXTRAKT)

Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus.
Liu JX1, Zhang Y1, Hu QP1, Li JQ2, Liu YT2, Wu QG1, Wu JG3, Lai XP4, Zhang ZD2, Li X5, Li G6.
Antiviral Res. 2017 Aug;144:34-43. doi: 10.1016/j.antiviral.2017.04.010. Epub 2017 Apr 29.

Evaluation of the virucidal effects of rosmarinic acid against enterovirus 71 infection via in vitro and in vivo study.
Lin WY1, Yu YJ1, Jinn TR2.
Virol J. 2019 Jul 31;16(1):94. doi: 10.1186/s12985-019-1203-z.

 

SANDDORN FRUCHTPULVER

Effect of Hippophae rhamnoides leaf extract against Dengue virus infection in human bloodderived macrophages.
Jain M1, Ganju L, Katiyal A, Padwad Y, Mishra KP, Chanda S, Karan D, Yogendra KM, Sawhney
RC.
Phytomedicine. 2008 Oct;15(10):793-9. doi: 10.1016/j.phymed.2008.04.017. Epub 2008 Jun 30.

 

SCHAFGARBE PFLANZENPULVER

In Vitro Anti-rotaviral Activity of Achillea kellalensis.
Taherkhani R1, Farshadpour F1, Makvandi M1.
Jundishapur J Nat Pharm Prod. 2013 Aug;8(3):138-43. Epub 2013 Jul 17.

 

SHIITAKE PILZEXTRAKT

Inhibition of Influenza Virus Infection by Lentinus edodes Mycelia Extract Through Its Direct Action and Immunopotentiating Activity.
Kuroki T1, Lee S2, Hirohama M3, Taku T1, Kumakura M1, Haruyama T3, Nagata K3, Kawaguchi
A1,2,3.
Front Microbiol. 2018 May 29;9:1164. doi: 10.3389/fmicb.2018.01164. eCollection 2018.

Antiviral and interferon-inducing activities of a new peptidomannan, KS-2, extracted from culture mycelia of Lentinus edodes.
Suzuki F, Suzuki C, Shimomura E, Maeda H, Fujii T, Ishida N.
J Antibiot (Tokyo). 1979 Dec;32(12):1336-45.

 

SILYMARIN (AUS MARIENDISTEL FRUCHTEXTRAKT) (BZW SILYBIN)

Silymarin efficacy against influenza A virus replication.
Song JH1, Choi HJ.
Phytomedicine. 2011 Jul 15;18(10):832-5. doi: 10.1016/j.phymed.2011.01.026. Epub 2011 Mar 5.

 

LÖWENZAHN WURZELEXTRAKT

Taraxacum officinale and Urtica dioica extracts inhibit dengue virus serotype 2 replication in vitro.
Flores-Ocelotl MR1,2,3, Rosas-Murrieta NH4, Moreno DA5, Vallejo-Ruiz V1, Reyes-Leyva
J1, Domínguez F6, Santos-López G7.
BMC Complement Altern Med. 2018 Mar 16;18(1):95. doi: 10.1186/s12906-018-2163-3.

 

SPIRULINA ALGENPULVER

Well-tolerated Spirulina extract inhibits influenza virus replication and reduces virus-induced mortality.
Chen YH1,2, Chang GK1, Kuo SM1, Huang SY1,2, Hu IC3, Lo YL1, Shih SR1,4,2,5.
Sci Rep. 2016 Apr 12;6:24253. doi: 10.1038/srep24253.

 

WERMUT BLATTEXTRAKT

Antiviral activities of Artemisia princeps var. orientalis essential oil and its α-thujone against norovirus surrogates.
Food Sci Biotechnol. 2017 Aug 28;26(5):1457-1461. doi: 10.1007/s10068-017-0158-3. eCollection
2017.