Everything about amino acids
There is still much to learn about amino acids
What are amino acids?
Amino acids (AS) are the building blocks from which proteins are built. They can bind to chains, like pearls, and once this chain contains more than 100 amino acids, it is called a protein.
Interestingly, the body does not need a certain amount of protein. But he primarily needs amino acids. It splits the consumed proteins in the stomach and small intestine in order to utilize the amino acids contained therein. Already split amino acids thus have better usability (biological value) than a protein still to be separated. Also, the release of the AS from plants is easier to accomplish than from animal protein. But the total amount of protein in animal food is slightly higher.
Why does the body use the amino acids?
So far, we have 20 (or 21) of these amino acids known that can form a protein. Assuming 21 different amino acids and a chain of 100 amino acids, this results in the possibility of combining 21hoch100.
As a result, the body is able to build up this variety of different proteins (antibodies, fingernails, muscles, etc.) from only 21 different protein building blocks. In 2005, an international symposium was held in Prague on "New therapeutic strategies through amino acid and protein therapy" (11).
"Unfortunately, there are neither suitable laboratory markers that indicate an exact need for amino acids, nor is taught in the education of medicine as to recognize an amino acid requirement, nor are there so far simple proven additions to the market. The blood analysis of each amino acid shows me only the current AS in the blood and does not take into account the need in the tissue. Matthias Welker
Amino acids are needed for more than just the muscles. Amino acids also form the basis of our connective tissue (subcutaneous tissue, elastic fibers, fasciae, connective tissue, etc.), play an important role as neurotransmitters, are essential for the immune system, and are building blocks of enzymes (we know 2,500 enzymes, but there are about 20,000 enzymes in the human organism), they are even involved in hormone production. In short, amino acids are essential for the functioning of body and psyche.
Amino acids are more than a muscle preparation or a fad. Amino acids are vital building blocks.
Are dietary supplements dangerous?
In this question, we are in a jungle of innumerable opinions:
"You have to take this, that helps you against * insert any problem here *." Or "Just do not take that, have just read how dangerous that is. That was in * insert sensational news page *. "
But what's wrong? The short answer: both are correct
But more precisely: There are countless studies for and against dietary supplements. But what is noticeable in the studies that are against dietary supplements? These are always so-called mono-preparations. So it is fed only a nutrient high doses.
Is it surprising that mono-preparations are not necessarily beneficial for your health? No, because nowhere in nature you only consume an isolated nutrient. A mono-preparation serves at most for short-term filling of an isolated acute deficiency, e.g. after poisoning, surgery, medication.
In nature - and also in Sanopoly - is always set to the synergy of the individual nutrients. Only then can the body benefit fully from a substitution and an overdose is avoided. The European Nutraceutical Association also expresses this idea in a detailed opinion on dietary supplements (1).
"Today, I am proud to say that only after years of research, medical monitoring and analysis of the well-being of many patients, Sanopoly offers such a meaningful and effective combination of nutrients. which is based on the actual needs of the people. "- Jan Veen Managing Director.
In addition, reference is made here to the statutory provisions with regard to dietary supplements, which also apply throughout the EU and thus make a harmful use impossible. The dosage recommendations are e.g. by the DGE (German Nutrition Society) chosen so that they do not harm with long-term intake. (2) In our observation, the recommendations in Germany are often even too low.
At Sanopoly, we make sure to follow these guidelines. In addition, our entire medical advisory board is constantly engaged in researching synergies and incorporating findings that are conducive to the human organism into the products.
Years of experience of therapists and patients have shown that there are no overdoses on Sanopoly products and no unwanted side effects. Not for nothing we are called Sanopoly.
"Sano" - healthy and "poly" - many
Are amino acids dangerous?
No - just the wrong rash application. For a long time, Sanopoly Medical Council has advised against consuming high doses of individual amino acids - that is contrary to our natural metabolism. An amino acid profile is needed that matches the human physique and daily needs.
Dr. Matthias Welker and many other colleagues have examined thousands of patients for their nutritional deficits over the last 20 years to identify this profile. In more than 80% of all patients, amino acids were the most frequent deficit. So the bigger danger is more a lack of amino acids than a short overdose.
An overdose of amino acids leads to a reduction of the unused portion. The sequence is e.g. an elevated uric acid level. In the long term, however, this can have negative consequences (gout, stress on the kidneys and liver, and more). But only if you regularly disbalances its amino acid balance with BCAA products (3).
Amino acids in general are absolutely harmless. On the contrary: The importance of amino acids is proven. Countless studies on different amino acids and their compounds are proving their positive effects (more on: What benefits do amino acids promise?).
Again, the synergy of the individual amino acids is simply to be considered. To get the full benefit, you should consume a balanced amino acid profile. This can be achieved through a healthy, high-protein diet. Main vegetable protein sources are recommended.
According to the above-mentioned investigations by Dr. med. Welker unfortunately manages the fewest people these days. It is almost impossible to have a balanced diet in today's day-to-day work, and to allow enough time for shopping, cooking and digesting.
With this knowledge and the importance of the amino acids, a healthy and effective supplement to the daily diet is recommended. A drug developed from the therapy experience supports & optimizes the body in its absorption and utilization, shows that it is complete, has an effect and does not increase urea and uric acid.
The composition of PriosaMINO has proven itself. With much effort we have reached the goal: an amino acid preparation that deals fairly and sustainably with human health.
Below we have worked up a few more studies.
What benefits do amino acids promise?
❖ This study (3) confirms our long-standing observation that branched-chain amino acids (so-called BCAAs) alone are not sufficient for the body. Also here is occupied. An entire amino acid spectrum is needed.
❖ In a 2007 study (4), scientists were able to prove with a high dose of glycine that it can be used to treat osteoarthritis and osteoporosis. All 600 participants have noticed an improvement.
❖ In a cell experiment (5), N-acetyl cysteine was able to completely abrogate oxidative damage. In addition, the positive effect on chronic lung disease was tested in this study (7)
❖ An increase in the plasma tryptophan concentration, according to this study (6), is significantly related to a reduced risk of cardiovascular disease.
❖ In one study (8) in Spain, glutamine has been shown to have anti-inflammatory effects. These were inflammatory findings in tumor patients with abdominal radiotherapy.
❖ In Singapore, a study (9) was conducted on pregnancy and sleep quality. A higher plasma tryptophan concentration has been shown to reduce the risk of poor sleep by 12 percent. This especially affects people with anxiety symptoms.
❖ Also in this study (10) the positive benefits of amino acids are discussed.
❖ An overdose is not actually an issue in practice. Further details are given in the study (11).
❖ As knee surgery, even complete knee replacement surgery, is expected to be more common, this study (12) from the US investigated the benefit of amino acids after surgery, with a positive result.
(1) European Nutraceutical Association - Dietary Supplements Orientation in the Jungle of Opinions http://www.enaonline.org/files/artikel/287/ENA%20Broschuere%20NEM_Web.pdf
(2) DIRECTIVE 2002/46 / EC OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 10 June 2002 on the approximation of the laws of the Member States relating to food supplements
(3) Robert R. Wolfe: Branched-chain amino acids and muscle protein synthesis in humans: myth or reality? Journal of the International Society of Sports Nutrition 2017, Received: 17 February 2017f
(4) Medical News Today Article, 10 Aug 2007: Glycine supplement helps prevent degenerative diseases such as arthrosis or osteoporosis
(5) T Ueno et al .: N-acetyl cysteine protects TMJ chondrocytes from oxidative stress; Journal of Dentral Research, Nov. 18, 2010
(6) Yu E, Ruiz-Canela M et al .: Increases in plasma tryptophan Are Associated with Incident Cardiovascular Disease in the Prevention of Dieta Mediterránea (PREDIMED) Study; J Nutr. 2017 Feb 8. pii: jn241711. doi: 10.3945 / jn.116.241711
(7) Amaral EP, Conceição EL et al .: N-acetyl-cysteine exhibits potent anti-mycobacterial activity in addition to its known anti-oxidative functions; BMC Microbiol. 2016 Oct 28; 16 (1): 251.
(8) Urbina JJO, San Miguel B et al .: Effects of Oral Glutamine on Inflammatory and Autophagic Responses in Cancer Patients Treated with Abdominal Radiotherapy: A Pilot Randomized Trial; Int J Med Sci. 2017 Sep 4; 14 (11): 1065-1071. doi: 10.7150 / ijms.20245. eCollection 2017.
(9) van Lee L, Cai S, Loy SL et al .: Relation of plasma tryptophan concentrations during pregnancy to maternal sleep and mental well-being: The GUSTO cohort; J Affect Disord. 2017 Aug 23; 225: 523-529
(10) Society of Nutritional Medicine and Dietetics e.V .; International Symposium »New Therapeutic Strategies through Amino Acid and Protein Therapy«, 25 to 27 February 2005 in Prague
(11) Willers, J., et al., Intake of Minerals from Food Supplements in a German Population-A Nationwide Survey, Food and Nutrition Sciences, Vol.6 Iss.2, p. 205 215.
(12) Dreyer, Hans C., et al., "Essential amino acid supplementation in patients following total knee arthroplasty", The Journal of Clinical Investigation, Epub published Ahead of print.